Thermoreceptors aresensory neuronsthat are activated by changes in temperature. They reside in the skin, liver, skeletal muscles, and in the hypothalamus. Some of them are activated by heat and others activated by cold, the latter being 3.5 times more common than the former.

通常寒冷温度感受器激活当tissue temperature falls below 25 °C , while warm thermoreceptors are most active when the temperature rises above 45. Their activation triggers anaction potentialthat transforms temperature changes into electrical information.