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Time to complete course: 15 min.
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发现当今可用的200多个学习模拟之一华体会赞助ac米兰
About Gene linkage and pedigree analysesVirtual Lab Simulation
该简短的针对性模拟是根据全长医学遗传学模拟进行的。
您是否知道您可以轻松地检查BRCA1或BRCA2中是否有小突变，这可能会使您更有可能发展乳腺癌？在此模拟中，您将学习基于从患者的DNA获得的数据构建血统，并发现突变与癌症发育风险之间的潜在关系，但使用链接分析。
Constructing pedigree
Your first task is to construct a family pedigree based on the gathered information. You will learn how to read a family pedigree and determine whether or not traits are hereditary. You will visit the hospital and talk with a doctor to learn about hereditary cancer and identify genes, such as BRCA1 and BRCA2 that can cause hereditary breast cancer in a family.
链接分析
接下来，您将到达实验室开始实验。您将使用靠近BRCA1和BRCA2基因的四个微卫星标记开始进行链接分析。然后，您将执行PCR来扩增微卫星标记，并通过使用凝胶电泳来解释结果。
Analyze the pedigree
In the end, by using the gel electrophoresis results, you will analyze the genotypes from family members. Will you be able to determine which gene is linked to hereditary breast cancer in this family?
Related Simulations
现在就开始
Put yourself in the place of a genetic counselor and find out if the daughter of a breast cancer patient is at a higher risk of developing breast cancer herself. You can help her by constructing a pedigree and finding the defective gene by using linkage analysis.
技术in Lab
- PCR
- 凝胶电泳
- 链接分析
学习目标
- Construct a pedigree using a polymerase chain reaction derived data
- 解释特定遗传突变与癌症发展风险之间的关系
仿真功能
Length- 15分钟
可访问模式- 可用的
语言- 英语
相关标准的示例
University
Early Stage Bachelors Level
早期大师级
EHEA First Cycle
美国大学1至4年
IB
Biology 3.1
AP
生物学单元5.4
Screenshots of Gene linkage and pedigree analysesVirtual Lab Simulation
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我们所有的模拟都华体会赞助ac米兰在笔记本电脑和台式计算机上运行，您可以播放我们的模拟，而无需安装任何浏览器插件。
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我们的虚拟实验室模拟ulations are aimed at university, college and high school level, within fields such as biology, biochemistry, genetics, biotechnology, chemistry, physics and more.
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