信号转导:How cells communicate

信号转导
完成课程的时间:32分钟。

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关于信号转导:How cells communicate虚拟实验室模拟

这是全长的“信号转导”模拟。对于较短的,更多的目标版本请参见下面的相关模拟。华体会赞助ac米兰

In this simulation, you will learn how tumor cells send signals to surrounding cells to help promote tumor growth, and how this signal is transmitted inside the cell.

通过蛋白质印迹分析患者样品

作为一家大型制药公司研发部门的研究人员,您的任务是检验以下假设:增加血管生长(也称为血管生成)在乳腺癌发育中起作用。为了调查这一想法,您将进行蛋白质印迹实验,以测试患者样品中血管内皮生长因子受体(VEGFR)表达的表达,与健康的组织样品相比。

Learn about VEGFR signal transduction

按照初始结果的解释,您将了解更多有关VEGFR(一种受体酪氨酸激酶(RTK))如何将外部信号传输到细胞内部的vegfr,以及这如何影响血管生成。您将能够在3D动画中遵循该过程。

Develop a strategy for breast cancer therapy

最后,您的任务是测试针对VEGFR信号的不同抑制剂。您将设计一种实验方法来测试该特定类别RTK的活性。

Will you be able to identify a promising new drug candidate for treating patients with breast cancer?

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Investigate the connection between blood vessel growth and cancer development, and use this knowledge to identify a promising treatment for breast cancer.

实验室中的技术

  • 蛋白质印迹
  • 细胞培养
  • Inhibitor treatment
  • Histology

Learning Objectives

最后的模拟,你可以…

  • 解释细胞内信号转导的原理和重要性
  • 解释受体酪氨酸激酶(RTK)细胞信号传导
  • Analyze dysregulated signal transduction in human cancer cells
  • Understand the connection between angiogenesis and tumor growth
  • Investigate the involvement of vascular endothelial growth factor receptor (VEGFR) signaling in human breast cancer

Simulation Features

长度- 32分钟
Languages– English, French, German, Spanish, Italian

Examples of Related Standards

大学

生命科学与第二年有关

NGSS

No direct alignment

IB

6.6: Hormones, Homeostasis and Reproduction

AP

Unit 4: Cell Communication and Cell Cycle

信号转导的屏幕截图:How cells communicate虚拟实验室模拟

Collaborators

Nina Porakishvili

生物医学科学系
威斯敏斯特大学

Caroline Smith

Department of Life Sciences
威斯敏斯特大学

How it works

A million dollar lab in your browser

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See detailed minimum requirements here.

Hundreds of hours of science learning content

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