尝试我们的实验室安全模拟
关于信号转导:How cells communicate虚拟实验室模拟
这是全长的“信号转导”模拟。对于较短的,更多的目标版本请参见下面的相关模拟。华体会赞助ac米兰
In this simulation, you will learn how tumor cells send signals to surrounding cells to help promote tumor growth, and how this signal is transmitted inside the cell.
通过蛋白质印迹分析患者样品
作为一家大型制药公司研发部门的研究人员,您的任务是检验以下假设:增加血管生长(也称为血管生成)在乳腺癌发育中起作用。为了调查这一想法,您将进行蛋白质印迹实验,以测试患者样品中血管内皮生长因子受体(VEGFR)表达的表达,与健康的组织样品相比。
Learn about VEGFR signal transduction
按照初始结果的解释,您将了解更多有关VEGFR(一种受体酪氨酸激酶(RTK))如何将外部信号传输到细胞内部的vegfr,以及这如何影响血管生成。您将能够在3D动画中遵循该过程。
Develop a strategy for breast cancer therapy
最后,您的任务是测试针对VEGFR信号的不同抑制剂。您将设计一种实验方法来测试该特定类别RTK的活性。
Will you be able to identify a promising new drug candidate for treating patients with breast cancer?
相关模拟华体会赞助ac米兰
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实验室中的技术
- 蛋白质印迹
- 细胞培养
- Inhibitor treatment
- Histology
Learning Objectives
最后的模拟,你可以…
- 解释细胞内信号转导的原理和重要性
- 解释受体酪氨酸激酶(RTK)细胞信号传导
- Analyze dysregulated signal transduction in human cancer cells
- Understand the connection between angiogenesis and tumor growth
- Investigate the involvement of vascular endothelial growth factor receptor (VEGFR) signaling in human breast cancer
Simulation Features
Examples of Related Standards
生命科学与第二年有关
No direct alignment
6.6: Hormones, Homeostasis and Reproduction
Unit 4: Cell Communication and Cell Cycle
Collaborators
Nina Porakishvili
生物医学科学系威斯敏斯特大学
Caroline Smith
Department of Life Sciences威斯敏斯特大学
How it works
A million dollar lab in your browser
在虚拟实验室模拟中执行实验以实现核心科学学习成果。华体会赞助ac米兰
All our simulations run on laptop and desktop computers, and you can play our simulations without having to install any browser plugins.
Hundreds of hours of science learning content
我们的虚拟实验室模拟针对大学,学院和高中层,在华体会赞助ac米兰生物学,生物化学,遗传学,生物技术,化学,物理学等领域。
With access to our simulations, you will have hundreds of hours of engaging, high-quality learning content available to you.


